Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00989 |
APCDD1 Protein, Mouse, Recombinant (His)
FP7019,HTS,Drapc1,HHS,Apcdd1<... |
Mouse | HEK293 Cells |
APCDD1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q3U128. | |||
TMPK-00311 |
APCDD1 Protein, Human, Recombinant (His)
HHS,B7323,Apcdd1,Drapc1,HYPT1... |
Human | HEK293 Cells |
APCDD1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 54.4 kDa and the accession number is Q8J025. | |||
TMPY-03046 |
APCDD1 Protein, Human, Recombinant (hFc)
HYPT1,B7323,adenomatosis polyposis coli down-regula... |
Human | HEK293 Cells |
Osteosarcoma (OS) is the most common type of bone tumor in children and adults. The expression of APCDD1, a Wnt antagonist, was reduced in OS tissues and cells compared to adjacent normal tissue and osteoblast cells, respectively. Mechanistically, this was due to increased levels of methylation in the promoter region of the APCDD1 gene. Consistently, the DNA methyltransferase inhibitor 5-AZA-dC, reduced DNA methylation in the APCDD1 promoter, and restored APCDD1 expression in OS tissue and cells... |