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Cat. No. | Product Name | Target | Signaling Pathways |
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T74978 | DPP IV/hCA II-IN-1 | ||
DPP IV/hCA II-IN-1 是一种有效的选择性二肽肽酶 IV (DPP IV) 和碳酸酐酶 (CA) 抑制剂,抑制 DPP IV 的 IC50值为 0.049 μM, 抑制 CA II、CA VB、CA VA、CA IX、CA I 和 CA IV 的 Ki 值分别为 0.0361、0.0428、0.0941、0.1328、0.2615 和 3.034 μM。 | |||
T21691 |
NVP DPP 728 dihydrochloride
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NVP-DPP728 是一种有效、可逆、腈依赖性二肽基肽酶 IV (DPP-IV)抑制剂,Ki 值为 11 nM。NVP-DPP728 可抑制胰高血糖素样肽-1 (GLP-1)的降解,从而增强响应于葡萄糖摄入的胰岛素释放。NVP-DPP728 可用于糖尿病研究。 | |||
T39481 |
NVP-DPP728 dihydrochloride
NVP-DPP728 dihydrochloride |
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NVP-DPP728 dihydrochloride is a highly potent, selective, and orally active inhibitor of dipeptidyl peptidase IV (DPP-IV), with a binding affinity (K i ) of 11 nM. This compound proves useful for investigating diabetes mellitus in research studies. |
Cat. No. | Product Name | Species | Expression System |
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TMPY-00732 |
Cathepsin C Protein, Human, Recombinant (His)
DPP-I,PLS,JP,cathepsin C,CPPI... |
Human | HEK293 Cells |
Cathepsins are proteases found in many types of cells conserved in all animals, which have a vital role in mammalian cellular turnover such as bone resorption. The lysosomal cysteine protease Cathepsin C (CTSC), also known as dipeptidyl peptidase I (DPPI/DPP1), activates a number of granule-associated serine proteases with pro-inflammatory and immune functions by removal of their inhibitory N-terminal dipeptides. This lysosomal exo-cysteine protease belonging to the peptidase C1 family. Active c... | |||
TMPH-02628 |
Cathepsin C Protein, Mouse, Recombinant (His & Myc)
Dipeptidyl transferase,Dipept... |
Mouse | E. coli |
Thiol protease. Has dipeptidylpeptidase activity. Can act as both an exopeptidase and endopeptidase. Can degrade glucagon. Plays a role in the generation of cytotoxic lymphocyte effector function. |