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Cat. No.	Product Name	Target	Signaling Pathways
T61828	DNA-PK-IN-8
	DNA-PK-IN-8（化合物DK1）是一种高效、选择性且口服活性的DNA依赖蛋白激酶 (DNA-PK) 抑制剂，其IC50值为0.8 nM。与Doxorubicin联合应用时，该化合物能在多种癌细胞中展现出协同的抗增殖效应，并能显著地抑制HL-60肿瘤生长。
T68192	OK-1035
	OK-1035 is a potent and selective DNA-PK inhibitor. When a synthetic peptide was used as a substrate, OK-1035 caused 50% inhibition of DNA-PK activity at 8 microM. OK-1035 inhibited the phosphorylation by DNA-PK of consensus peptide as well as that of recombinant human wild type-p53. Kinetic studies indicated that OK-1035 inhibited DNA-PK activity in an ATP-competitive manner.
T61587	ATR-IN-15
	ATR-IN-15 (compound 1) is a highly potent and orally active inhibitor of ATR kinase with an IC50 of 8 nM. Additionally, ATR-IN-15 demonstrates inhibitory activity against several targets, including human colon tumor cells LoVo, DNA-PK, and PI3K, with IC50 values of 47, 663, and 5131 nM, respectively [1].