Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01211 |
DGUOK Protein, Human, Recombinant (His & SUMO)
Deoxyguanosine kinase, mitochondrial,Deoxyadenosine kinase, ... |
Human | E. coli |
Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents. |