Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9640 |
Diethylnorspermine HCl
Diethylnorspermine tetrahydrochloride,N1,N11-Diethylnorspermine tetrahydrochloride,DENSPM tetrahydrochloride |
Others | Others |
Diethylnorspermine HCl (N1,N11-Diethylnorspermine tetrahydrochloride) 可有效诱导 SSAT (亚精胺/精胺N1-乙酰转移酶) mRNA,并有效稳定 SSAT 酶活性。 | |||
T70803 |
ZD-6888
|
Others | Others |
ZD-6888 is an angiotensin type 1 receptor antagonist potentially for the treatment of hypertension. | |||
T70805 |
Diethylnorspermine HBr
|
Others | Others |
Diethylnorspermine, also known as DENSPM, BE-333, DE-333 and N(1),N(11)-Diethylnorspermine, is a highly potent known inducer of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT). A designed polyamines (PAs) analog which induces cell cycle arrest, inhibits proliferation and induces apoptosis in melanoma, breast, prostate, lung and colon cancer cells.. | |||
T60348 |
N1,N11-Diethylnorspermine
|
Others | Others |
N1,N11-Diethylnorspermine (DENSPM) 是一种有效的抗癌剂。N1,N11-Diethylnorspermine 是一种精胺类似物,可激活多胺分解代谢。N1,N11-Diethylnorspermine 诱导细胞色素 c 从线粒体中释放,导致 caspase 3的激活。N1,N11-Diethylnorspermine 通过诱导亚精胺/精胺 N1- 乙酰转移酶 (SSAT) 结合产生过氧化氢杀灭多形胶质母细胞瘤 (GBM) 细胞。 |