Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03521 |
DcR3 Protein, Human, Recombinant (hFc)
DCR3,tumor necrosis factor receptor superf... |
Human | Baculovirus Insect Cells |
Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) also known as DcR3(Decoy Receptor 3) and M68 is the tumor necrosis factor receptor superfamily. DcR3/TNFRSF6B belongs to the tumor necrosis factor receptor superfamily. The encoded protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death. It acts as a decoy receptor that competes with death receptors for ligand binding. Over-expression of this gene has been noted in gastrointestinal tract tu... | |||
TMPK-01378 |
IL-12B Protein, Cynomolgus, Recombinant (His)
CLMF2,NKSF2,CLMF,CLMF p40,IL-12B,IL-12 subunit p40,NKS |
Cynomolgus | HEK293 Cells |
Interleukin (IL)‑12B, which encodes the p40 subunit common to IL‑12 and IL‑23, as one of the genes for which expression in fibroblast‑like synoviocytes from patients with rheumatoid arthritis (RA‑FLS) is induced by DcR3.Decoy receptor 3 (DcR3) competitively binds to three ligands, Fas ligand, lymphotoxin‑related inducible ligand that competes for glycoprotein D binding to herpesvirus entry mediator on T cells and tumor necrosis factor‑like ligand 1A (TL1A), to prevent their effects. Recent studi... | |||
TMPH-00545 |
Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc)
|
EBV | E. coli |
Immediate-early transcription factor that controls the initiation of viral lytic gene expression and lytic reactivation from latency. Triggers lytic replication, and initiates a cellular senescence program in epithelial cells. Upregulates human DCR3/TNFRSF6B by directly binding to its receptor. Epstein-Barr virus (strain GD1) BRLF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 34.9 kDa and the accession number is Q3KS... |