Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14996 |
Congo Red
刚果红,Direct Red 28 |
Others | Others |
Congo Red (Direct Red 28) 是偶氮染料指示剂,在 pH 3.0的环境下呈紫罗兰色,在 pH5.0的环境下呈红色,常用于组织切片中淀粉样蛋白的测定。 | |||
T22972 |
Methoxy-X04
|
Others | Others |
Methoxy-X04, a derivative of Congo red and Chrysamine-G, is a brain-permeable fluorescent probe for amyloid-β (Aβ). | |||
T63691 |
Chrysamine G
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Chrysamine G 是一种刚果红的羧酸类似物,对 Aβ 诱导的 PC12 细胞毒性具有抑制作用。Chrysamine G 能够用作阿尔茨海默病中淀粉样蛋白沉积的探针。 | |||
T75361 | BSB | ||
BSB,一种刚果红衍生的荧光探针,既与细胞外淀粉样β蛋白发生结合,也能与由异常tau蛋白与突触核蛋白组成的细胞内病变相结合,是作为阿尔茨海默病原型成像剂的代表。 | |||
T37370 |
Amyloid-β (25-35) Peptide (human) (trifluoroacetate salt)
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Amyloid-β (25-35) (Aβ (25-35)) is an 11-residue fragment of the Aβ protein that retains the physical and biological characteristics of the full length peptide. It forms fibrils that react to thioflavin T and Congo red and are organized in a cross-β arrangement of β-strands similar to Aβ (1-40) and Aβ (1-42) fibrils. Aggregated Aβ (25-35) decreases the viability of rat adrenal PC12 cells. It also decreases the viability of primary rat cortical neurons at concentrations ranging from 1 nM to 30 μM.... |