Cat. No. | Product Name | Target | Signaling Pathways |
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T36467 |
Chrysomycin A
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Chrysomycin A 是一种可来自链霉菌的抗生素。在胶质母细胞瘤中,Chrysomycin A 通过 Akt/GSK-3β/β-catenin 信号通路抑制癌细胞的增殖、迁移和侵袭。 表现出抗肿瘤和抗结核和 MRSA 活性。 | |||
T36892 | 4'-Acetyl Chrysomycin A | ||
4'-Acetyl chrysomycin A is a bacterial metabolite and derivative of chrysomycin A that has been found inStreptomycesand has antibacterial and anticancer activities.1It is active against strains of methicillin-resistantS. aureus(MRSA) and vancomycin-resistant strains ofE. faecalisandE. faecium(MICs = 0.5-2 μg/ml for all). 4'-Acetyl chrysomycin A is cytotoxic against a panel of human cancer cell lines, including doxorubicin-sensitive or -resistant cells (IC50s = 0.085-0.26 and 3.4-16 ng/ml, respec... |