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4

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T25294 DCFBC F-18

18F-DCFBC

DCFBC F-18 is a radioconjugate containing a low molecular weight tracer, DCFBC, specific for prostate-specific membrane antigen (PSMA) and labeled with the positron-emitting isotope F 18 with potential prostate tumor imaging upon positron emission tomogra
T25293 DCFBC

DCFBC is a low-molecular-weight radiotracer. It targets prostate-specific membrane antigen (PSMA).
T74683 IONIS-FB-LRx

IONIS-FB-LRx 是一种靶向补体因子 B (CFB) 的特殊反义寡核苷酸(ASO)。IONIS-FB-LRx 能有效降低 CFB 的循环水平。IONIS-FB-LRx 可用于地理萎缩 (GA) 研究。
T11864 Iptacopan

LNP023

Others Others
Iptacopan (LNP023) 是一种与factor B 亲和力较高的抑制剂。

化合物

DCFBC F-18
Cat.No: T25294
Synonym: 18F-DCFBC
Target:
DCFBC
Cat.No: T25293
Synonym:
Target:
IONIS-FB-LRx
Cat.No: T74683
Synonym:
Target:
Iptacopan
Cat.No: T11864
Synonym: LNP023
Target: Others
Cat. No. Product Name Species Expression System
TMPY-04921 Complement factor B/CFB Protein, Human, Recombinant (His)

ARMD14,GBG,AHUS4,PBF2,complement factor B,FBI12,BF,H2-Bf,BFD...

Human HEK293 Cells
Complement factor B/CFB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.5 kDa and the accession number is AAH04143.1.
TMPH-02607 Complement factor B Protein, Mouse, Recombinant (His)

C3/C5 convertase,Complement factor B,Cfb,Bf,H2-Bf

Mouse E. coli
Factor B which is part of the alternate pathway of the complement system is cleaved by factor D into 2 fragments: Ba and Bb. Bb, a serine protease, then combines with complement factor 3b to generate the C3 or C5 convertase.
TMPH-03038 Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)

Cobra venom factor,Complement C3 homolog,CVFk,CVF

Naja kaouthia E. coli
Complement-activating protein in cobra venom. It is a structural and functional analog of complement component C3b, the activated form of C3. It binds factor B (CFB), which is subsequently cleaved by factor D (CFD) to form the bimolecular complex CVF/Bb. CVF/Bb is a C3/C5 convertase that cleaves both complement components C3 and C5. Structurally, it resembles the C3b degradation product C3c, which is not able to form a C3/C5 convertase. Unlike C3b/Bb, CVF/Bb is a stable complex and completely re...

重组蛋白

Complement factor B/CFB Protein, Human, Recombinant (His)
Cat.No: TMPY-04921
Species: Human
Expression System: HEK293 Cells
Complement factor B Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02607
Species: Mouse
Expression System: E. coli
Cobra venom factor Protein, Naja kaouthia, Recombinant (His & SUMO)
Cat.No: TMPH-03038
Species: Naja kaouthia
Expression System: E. coli
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