Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T17819 |
Thalidomide-O-amido-C8-NH2
E3 Ligase Ligand-Linker Conjugates 20,Cereblon Ligand-Linker Conjugates 2 |
Others | Others |
Thalidomide-O-amido-C8-NH2 (Cereblon Ligand-Linker Conjugates 2) is a synthesized E3 ligase ligand-linker conjugate comprising a Thalidomide-based cereblon ligand and a linker. This compound is useful in the synthesis of PROTACs, as per reference [1]. | |||
T17906 |
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc
E3 Ligase Ligand-Linker Conjugates 53,Cereblon Ligand-Linker Conjugates 20 |
Others | Others |
Pomalidomide-amido-C4-amido-PEG2-C2-NH-Boc is a novel synthesized conjugate compound functioning as an E3 ligase ligand-linker in PROTAC technology. This compound incorporates a Pomalidomide-derived cereblon ligand, which binds selectively to the E3 ligase cereblon, and a 2-unit PEG linker, which provides stability and flexibility to the conjugate. |