Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T25201 |
Camsirubicin
|
Others | Others |
Camsirubicin is a drug candidate of antineoplastic. | |||
T69669 |
Camsirubicin HCl
|
Others | Others |
Camsirubicin, also known as GPX-150, MNPR-201, and CNDO1011, is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis. | |||
T69668 |
CCW 28-3
|
Others | Others |
CCW 28-3 is a novel potent covalent BRD4 degrader, degrading BRD4 in a proteasome- and RNF4-dependent manner without inhibiting RNF4 autoubiquitination activity. |