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1

抑制剂 & 化合物

4

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T78784 RIPK3-IN-3

RIPK3-IN-3(化合物20)是一种针对受体相互作用蛋白激酶RIPK3的选择性抑制剂,其IC50为10 nM。它通过抑制p-MLKL的寡聚化作用来阻止RIPK3介导的MLKL磷酸化以及随后的坏死性凋亡。此外,RIPK3-IN-3还能降低CXCL5的分泌,并抑制AsPC-1细胞的迁移和侵袭。

化合物

RIPK3-IN-3
Cat.No: T78784
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-03050 CXCL5 Protein, Human, Recombinant

ENA-78,SCYB5,chemokine (C-X-C motif) ligand 5

Human E. coli
CXCL5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 7.8 kDa and the accession number is P42830.
TMPH-01163 CXCL5 Protein, Human, Recombinant (His)

Epithelial-derived neutrophil-activating protein 78,SCYB...

Human E. coli
CXCL5 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-04790 CXCL5 Protein, Mouse, Recombinant (His)

AMCF-II,GCP-2,Scyb6,LIX,chemokine (C-X-C motif) ligand 5...

Mouse P. pastoris (Yeast)
CXCL5 Protein, Mouse, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.4 kDa and the accession number is P50228.
TMPJ-01060 CXCL6 Protein, Human, Recombinant (His)

SCYB6,Chemokine Alpha 3,CKA-3,GCP2,GCP-2,C-X-C Motif Chemoki...

Human HEK293 Cells
Chemokine (C-X-C-Motif) Ligand 6 (CXCL6) is a small cytokine belonging to the CXC chemokine family. It is a potent neutrophil chemotactic and activating factor and it exhibits extensive similarity to other CXC chemokines such as IL-8 and ENA-78. CXCL6 can promote the release of MMP-9 from granulocytes indicating its potential role as an inflammatory mediator. It functionally uses both of the IL-8/CXCL8 receptors to chemoattract neutrophils but that is structurally most related to epithelial cell...

重组蛋白

CXCL5 Protein, Human, Recombinant
Cat.No: TMPY-03050
Species: Human
Expression System: E. coli
CXCL5 Protein, Human, Recombinant (His)
Cat.No: TMPH-01163
Species: Human
Expression System: E. coli
CXCL5 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-04790
Species: Mouse
Expression System: P. pastoris (Yeast)
CXCL6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01060
Species: Human
Expression System: HEK293 Cells
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