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2

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T39337	Ezurpimtrostat
	Ezurpimtrostat (compound 2-2) is used for the study of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases.
T62882	Ezurpimtrostat hydrochloride GNS561 hydrochloride	Antiviral	Immunology/Inflammation
	Ezurpimtrostat hydrochloride (GNS561 hydrochloride) 是一种可口服的棕榈酰蛋白硫酯酶-1 抑制剂，具有抗纤维化、抗病毒和抗癌作用，通过与棕榈酰蛋白硫酯酶相互作用抑制晚期自噬和剂量依赖性增大溶酶体的积聚来阻断癌细胞增殖。Ezurpimtrostat hydrochloride 可用于研究肝癌。

化合物

Cat.No: T39337

Ezurpimtrostat hydrochloride

Cat.No: T62882

Synonym: GNS561 hydrochloride

Target: Antiviral

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00497	CTSB Protein, Human, Recombinant (His) APPS,CPSB,APP Secretase,Cathepsin B1,Cathepsin B,CTSB	Human	HEK293 Cells
	Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor...
TMPH-01059	Cathepsin B Protein, Human, Recombinant (GST) Cathepsin B1,APPS,Cathepsin B,CPSB,APP secretase,CTSB	Human	E. coli
	Thiol protease which is believed to participate in intracellular degradation and turnover of proteins. Cleaves matrix extracellular phosphoglycoprotein MEPE. Involved in the solubilization of cross-linked TG/thyroglobulin in the thyroid follicle lumen. Has also been implicated in tumor invasion and metastasis. Cathepsin B Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.6 kDa and the accession number is P07858.
TMPH-00775	IFN gamma Protein, Goat, Recombinant (His & Myc)	Goat	E. coli
	Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activati...

重组蛋白

CTSB Protein, Human, Recombinant (His)

Cat.No: TMPJ-00497

Species: Human

Expression System: HEK293 Cells

Cathepsin B Protein, Human, Recombinant (GST)

Cat.No: TMPH-01059

Species: Human

Expression System: E. coli

IFN gamma Protein, Goat, Recombinant (His & Myc)

Cat.No: TMPH-00775

Species: Goat

Expression System: E. coli

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