Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01241 |
CARHSP1 Protein, Human, Recombinant
CSDC1,CRHSP24,CRHSP-24 |
Human | E. coli |
Ca2+-regulated heat-stable protein of 24 kDa (CRHSP-24) is a serine phosphoprotein originally identified as a physiological substrate for the Ca2+-calmodulin regulated protein phosphatase calcineurin (PP2B). CRHSP-24 is a paralog of the brain-specific mRNA-binding protein PIPPin and was recently shown to interact with the STYX/dead phosphatase protein in developing spermatids. | |||
TMPY-03499 |
CARHSP1 Protein, Human, Recombinant (His)
CSDC1,calcium regulated heat stable protei... |
Human | E. coli |
CARHSP1 is a biomarker for diabetic complications. Adenovirus-mediated CARHSP1 overexpression and siRNA-mediated knockdown experiments were performed to characterize the role of CARHSP1 in the regulation of gluconeogenic gene expression. CARHSP1 is regulated by nutrient status in the liver and functions at the transcriptional level to negatively regulate gluconeogenic genes, including the glucose-6-phosphatase catalytic subunit (G6Pc) and phosphoenolpyruvate carboxykinase 1 (PEPCK1). In add... |