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Targets Recommended: PROTACs

1

抑制剂 & 化合物

5

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T74994 SJ988497

PROTACs PROTAC
SJ988497是一种PROTACJAK2降解剂,有效地抑制CRLF2重排(CRLF2r)细胞增殖并降解CRBN新底物GSPT1。该化合物由Ruxolitinib衍生物、连接子以及CRBN配体Pomalidomide构成,可作为急性淋巴细胞白血病(ALL)研究用途。

化合物

SJ988497
Cat.No: T74994
Synonym:
Target: PROTACs
Cat. No. Product Name Species Expression System
TMPY-05242 CRLF2/TSLPR Protein, Human, Recombinant (His)

CRL2,CRLF2Y,TSLPR,cytokine recept...

Human HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is D0E2W4.
TMPK-01331 TSLPR Protein, Cynomolgus, Recombinant (His)

CRL2,CRLF2,IL-XR,CRLF

Cynomolgus HEK293 Cells
Thymic stromal lymphopoietin (TSLP) is an interleukin-7 (IL-7) like cytokine, which plays an important role in the regulation of immune responses to allergens. TSLP binds to a heterodimeric receptor complex composed of the IL-7 receptor alpha chain (IL-7Ralpha) and the TSLP receptor (TSLPR, also known as CRLF2).
TMPY-05769 CRLF2/TSLPR Protein, Human, Recombinant (hFc)

CRLF2Y,cytokine receptor-like factor 2...

Human HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.91 kDa and the accession number is D0E2W4.
TMPJ-00530 TSLPR Protein, Mouse, Recombinant (hFc)

CRLF2,CRL2 cytokine receptor,TSLP...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 62-88 KDa and the accession number is AAH23788.1.
TMPJ-00531 TSLPR Protein, Mouse, Recombinant (His)

Cytokine receptor-like 2,Thymic stromal-derived lym...

Mouse HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-40 KDa and the accession number is AAH23788.1.

重组蛋白

CRLF2/TSLPR Protein, Human, Recombinant (His)
Cat.No: TMPY-05242
Species: Human
Expression System: HEK293 Cells
TSLPR Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01331
Species: Cynomolgus
Expression System: HEK293 Cells
CRLF2/TSLPR Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05769
Species: Human
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00530
Species: Mouse
Expression System: HEK293 Cells
TSLPR Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00531
Species: Mouse
Expression System: HEK293 Cells
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