Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01120 |
COL4A2 Protein, Human, Recombinant (His)
COL4A2,Collagen alpha-2(IV) chain |
Human | E. coli |
COL4A2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.3 kDa and the accession number is P08572. | |||
TMPH-02590 |
COL4A2 Protein, Mouse, Recombinant (His)
COL4A2,Collagen alpha-2(IV) chain |
Mouse | E. coli |
Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.; Canstatin, a cleavage product corresponding to the collagen alpha 2(IV) NC1 domain, possesses both anti-angiogenic and anti-tumor cell activity. It inhibits proliferation and migration of endothelial cells, reduces mitochondrial membrane potential, and induces apoptosis. Specifically induces Fas-dependent apoptos... |