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Search Results for " cn1 "

6

抑制剂 & 化合物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T63647	DCN1-UBC12-IN-1
	DCN1-UBC12-IN-1 是有效的、特异性的 DCN1-UBC12 抑制剂，其 IC50 值为 2.86 nM，具有抗心脏成纤维化活性。
T9302	CN128 hydrochloride
	CN128 hydrochloride 是一种CN128衍生物，是一种具有口服活性和选择性的铁螯合剂。CN128是一种新型且具有口服活性的羟吡啶酮铁螯合剂，可用于研究 β-地中海贫血。
T68324	KCN1
	KCN1, a novel synthetic sulfonamide, is a HIF pathway inhibitor with potential anticancer activity in vitro and in vivo anti-pancreatic cancer activities and preclinical pharmacology. KCN1 specifically inhibited HIF reporter gene activity in several glioma cell lines at the nanomolar level. KCN1 also downregulated transcription of endogenous HIF-1 target genes, such as VEGF, Glut-1, and carbonic anhydrase 9, in a hypoxia-responsive element (HRE)-dependent manner. KCN1 potently inhibited the grow...
T63820	DCN1-UBC12-IN-2
	DCN1-UBC12-IN-2 是有效的、特异性的 DCN1-UBC12 抑制剂，其 IC50 值为 9.55 nM。DCN1-UBC12-IN-2 能够特异性靶向 DCN1-UBC12 相互作用，减缓 Ang II 诱导的心脏成纤维细胞活化。
T10684L	Carnostatine hydrochloride SAN9812 hydrochloride	Others	Others
	Carnostatine hydrochloride (SAN9812 hydrochloride) 是一种有效的选择性肌肽酶 1 (CN1) 抑制剂，对人重组 CN1 的Ki 值为 11 nM。Carnostatine hydrochloride 可用于治疗糖尿病性肾病 (DN) 。
T10684	Carnostatine SAN9812	Others	Others
	Carnostatine (SAN9812) 是一种有效的选择性肌肽酶 1 (CN1) 抑制剂，对人重组 CN1 的Ki 值为 11 nM。Carnostatine 可用于治疗糖尿病性肾病 (DN) 。

化合物

DCN1-UBC12-IN-1

Cat.No: T63647

CN128 hydrochloride

Cat.No: T9302

Cat.No: T68324

DCN1-UBC12-IN-2

Cat.No: T63820

Carnostatine hydrochloride

Cat.No: T10684L

Synonym: SAN9812 hydrochloride

Target: Others

Cat.No: T10684

Synonym: SAN9812

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02733	CNDP1 Protein, Mouse, Recombinant (His) AI746433,carnosine dipeptidase 1 (metallopeptidase ...	Mouse	HEK293 Cells
	CNDP1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.5 kDa and the accession number is Q8BUG2.
TMPY-00719	CNDP1 Protein, Human, Recombinant (His) HsT2308,CN1,carnosine dipeptidase 1	Human	HEK293 Cells
	CNDP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.3 kDa and the accession number is Q96KN2.
TMPY-01028	Ficolin 1/FCN1 Protein, Human, Recombinant (His) FCNM,FCN1,ficolin 1,F	Human	HEK293 Cells
	Ficolin 1/FCN1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 33.6 kDa and the accession number is O00602.
TMPH-02848	CYR61/CCN1 Protein, Mouse, Recombinant (His) CCN1,IGFBP-10,CCN family...	Mouse	E. coli
	CYR61/CCN1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 42.6 kDa and the accession number is P18406.
TMPH-02030	Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His) is expressed in Yeast.
TMPY-04707	Ficolin 1/FCN1 Protein, Rhesus, Recombinant (hFc) ficolin 1,FCNA,FCN1	Rhesus	HEK293 Cells
	Ficolin 1/FCN1 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 59.1 kDa and the accession number is XP_001098002.1.
TMPH-02215	TCN1 Protein, Human, Recombinant (His)	Human	P. pastoris (Yeast)
	Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPH-02655	Ficolin 1/FCN1 Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Ficolin 1/FCN1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.5 kDa and the accession number is O70165.
TMPH-01068	CYR61/CCN1 Protein, Human, Recombinant (His & SUMO) IBP-10,GIG1,IGFBP-10,Insulin-like...	Human	E. coli
	CYR61/CCN1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 55.4 kDa and the accession number is O00622.
TMPY-01679	LCN1 Protein, Human, Recombinant (His) TLC,MGC71975,TP,VEGP,Lipocalin 1,PMFA	Human	HEK293 Cells
	Lipocalin-1, also known as Von Ebner gland protein, VEG protein, Tear Prealbumin, VEGP, Tear lipocalin, and LCN1 is a secreted protein that belongs to the calycin superfamily and Lipocalin family. Human Lipocalin-1 / VEGP was originally described as a major protein of human tear fluid, which was thought to be tear specific. Lipocalin-1 / VEGP is identical to lingual von Ebner's gland protein and is also produced in the prostate, nasal mucosa, and tracheal mucosa. Homologous proteins have been fo...
TMPH-02216	TCN1 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Binds vitamin B12 with femtomolar affinity and protects it from the acidic environment of the stomach.
TMPJ-00658	CYR61/CCN1 Protein, Human, Recombinant (hFc) Cysteine-rich angiogenic inducer 61,IGFBP1...	Human	HEK293 Cells
	Protein CYR61, also known as CCN family member 1, Cysteine-rich angiogenic inducer 61,Insulin-like growth factor-binding protein 10 , GIG1, CYR61, CCN1 and IGFBP10, belongs to the CCN family, CYR61 is a secreted protein and contains one CTCK (C-terminal cystine knot-like) domain,one IGFBP N-terminal domain,one TSP type-1 domain and one VWFC domain. CYR61 promotes cell proliferation, chemotaxis, angiogenesis and cell adhesion. CYR61 plays important roles in inflammation and tissue repair. CYR61 ...
TMPH-02118	SCN1A Protein, Human, Recombinant (His)	Human	E. coli
	Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. Plays a key role in brain, probably by regulating the moment when neurotransmitters are released in neurons. Involved in sensory perception of mechanical pain: activation in somatosensory neur...

重组蛋白

CNDP1 Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02733

Species: Mouse

Expression System: HEK293 Cells

CNDP1 Protein, Human, Recombinant (His)

Cat.No: TMPY-00719

Species: Human

Expression System: HEK293 Cells

Ficolin 1/FCN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01028

Species: Human

Expression System: HEK293 Cells

CYR61/CCN1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02848

Species: Mouse

Expression System: E. coli

Reticulocalbin-1/RCN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02030

Species: Human

Expression System: P. pastoris (Yeast)

Ficolin 1/FCN1 Protein, Rhesus, Recombinant (hFc)

Cat.No: TMPY-04707

Species: Rhesus

Expression System: HEK293 Cells

TCN1 Protein, Human, Recombinant (His)

Cat.No: TMPH-02215

Species: Human

Expression System: P. pastoris (Yeast)

Ficolin 1/FCN1 Protein, Mouse, Recombinant (His)

Cat.No: TMPH-02655

Species: Mouse

Expression System: E. coli

CYR61/CCN1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01068

Species: Human

Expression System: E. coli

LCN1 Protein, Human, Recombinant (His)

Cat.No: TMPY-01679

Species: Human

Expression System: HEK293 Cells

TCN1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02216

Species: Human

Expression System: E. coli

CYR61/CCN1 Protein, Human, Recombinant (hFc)

Cat.No: TMPJ-00658

Species: Human

Expression System: HEK293 Cells

SCN1A Protein, Human, Recombinant (His)

Cat.No: TMPH-02118

Species: Human

Expression System: E. coli

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