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Cat. No. Product Name Species Expression System
TMPH-01762 CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO)

CHRNA3,NACHRA3,Neuronal acetylcho...

Human E. coli
After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 44.6 kDa and the accession number is P32297.
TMPH-00430 VxXIIC Protein, Conus vexillum, Recombinant (His & Myc & SUMO)

Conus vexillum E. coli
Alpha-conotoxins act on postsynaptic membranes, they bind to the nicotinic acetylcholine receptors (nAChR) and thus inhibit them. This toxin specifically blocks mammalian neuronal nAChR of the alpha-7/CHRNA7, alpha-3-beta-2/CHRNA3-CHRNB2 and alpha-4-beta-2/CHRNA4-CHRNB2 subtypes. VxXXA and VxXXB inhibit alpha-7/CHRNA7 and alpha-3-beta-2/CHRNA3-CHRNB2 nAChR more efficiently than VxXXC. VxXXB is the most effective at inhibiting alpha-4-beta-2/CHRNA4-CHRNB2 nAChR, followed by VxXXC and VxXXA. VxXII...
TMPY-04321 CHRNA5 Protein, Human, Recombinant (His)

cholinergic receptor, nicotinic, α5 (neuronal),cholinergic r...

Human HEK293 Cells
Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer. CHRNA5 may influence susceptibility to lung cancer among Han smokers. Genetic variation in nicotinic receptor alpha 5 (CHRNA5) has been associated with increa...
TMPH-03037 Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc)

Alpha-CT,Alpha-Ctx,Alpha-EPTX-Nk2a,Long neurotoxin 1,Alpha-C...

Naja kaouthia E. coli
Monomer: binds with high affinity to muscular (alpha-1-beta-1-gamma-delta/CHRNA1-CHRNB1-CHRNG-CHRND) nAChR (tested on Torpedo californica, Kd=0.2-4.5 nM) and neuronal alpha-7/CHRNA7 nicotinic acetylcholine receptors (Kd=13-105 nM). Also inhibits GABA(A) channels. Heteropentamer targets studied are composed of alpha-1-beta-3-gamma-2 (GABRA1-GABRB3-GABRG2) subunits (IC(50)=236 nM), alpha-1-beta-2-gamma-2 (GABRA1-GABRB2-GABRG2) subunits (IC(50)=469 nM), alpha-2-beta-2-gamma-2 (GABRA2-GABRB2-GABRG2)...

重组蛋白

CHRNA3 Protein, Human, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-01762
Species: Human
Expression System: E. coli
VxXIIC Protein, Conus vexillum, Recombinant (His & Myc & SUMO)
Cat.No: TMPH-00430
Species: Conus vexillum
Expression System: E. coli
CHRNA5 Protein, Human, Recombinant (His)
Cat.No: TMPY-04321
Species: Human
Expression System: HEK293 Cells
Alpha-cobratoxin Protein, Naja kaouthia, Recombinant (GST & His & Myc)
Cat.No: TMPH-03037
Species: Naja kaouthia
Expression System: E. coli
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