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Cat. No. Product Name Species Expression System
TMPH-01715 CHRM2 Protein, Human, Recombinant (His)

CHRM2,Muscarinic acetylcholine receptor M<...

Human E. coli
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition. Signaling promotes phospholipase C activity, leading to the release of inositol trisphosphate (IP3); this then triggers calcium ion release into the cytosol. CHRM2 Protein, Human, Recombinant (His) is expressed in E. col...
TMPH-02020 RGS17 Protein, Human, Recombinant (GST)

Human E. coli
Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Binds selectively to GNAZ and GNAI2 subunits, accelerates their GTPase activity and regulates their signaling activities. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins. R...

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CHRM2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01715
Species: Human
Expression System: E. coli
RGS17 Protein, Human, Recombinant (GST)
Cat.No: TMPH-02020
Species: Human
Expression System: E. coli
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