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Cat. No. Product Name Target Signaling Pathways
T71902 CHEMBL94431

CHEMBL94431 is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase.
T69985 Lifirafenib HCl

Lifirafenib, also known as Beigene-283, is a Novel potent and selective RAF Kinase and EGFR inhibitor. BGB-283-displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 potently inhibits B-RAFV600E-activated ERK phosphorylation and cell proliferation. It demonstrates selective cytotoxicity and preferentially inhibits proliferation of cancer cells harbouring B-RAFV600E and EGFR mutation/amplification. In B-RAFV600E CRC cell lines, BGB-283 effectively inhibits the ...

化合物

CHEMBL94431
Cat.No: T71902
Synonym:
Target:
Lifirafenib HCl
Cat.No: T69985
Synonym:
Target:
TargetMol Loading
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