Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04022 |
BOLA1 Protein, Human, Recombinant (His)
CGI-143,bolA family member 1 |
Human | E. coli |
BOLA1 is a mitochondrial protein that counterbalances the effect of L-buthionine-(S,R)-sulfoximine (BSO)-induced glutathione (GSH) depletion on the mitochondrial thiol redox potential. Furthermore, overexpression of BOLA1 nullifies the effect of BSO and S-nitrosocysteine on mitochondrial morphology. Conversely, knockdown of the BOLA1 gene increases the oxidation of mitochondrial thiol groups. Supporting a role of BOLA1 in controlling the mitochondrial thiol redox potential is that BOLA1 ortholog... |