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Cat. No. Product Name Target Signaling Pathways
T40289 CDK12-IN-6

CDK12-IN-6

CDK12-IN-6, a pyrazolotriazine compound, is a powerful inhibitor of CDK12. Its inhibitory activity is significant with an IC50 value of 1.19 μM when tested at high ATP concentration (2 mM). Notably, CDK12-IN-6 does not exhibit any inhibitory effect on CDK2/Cyclin E (IC50 >20 μM) and CDK9/Cyclin T1 (IC50 >20 μM) when tested under the same high ATP conditions (2 mM) (WO2021116178A1).

化合物

CDK12-IN-6
Cat.No: T40289
Synonym: CDK12-IN-6
Target:
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