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Cat. No. Product Name Target Signaling Pathways
T40290 CDK12-IN-5

CDK12-IN-5

CDK12-IN-5 is a pyrazolotriazine compound that effectively inhibits CDK12, with an IC50 value of 23.9 nM at a high ATP concentration of 2 mM. However, CDK12-IN-5 does not exhibit inhibitory effects on CDK2/Cyclin E (IC50 = 173 μM) and CDK9/Cyclin T1 (IC50 = 127 μM) at the same high ATP concentration of 2 mM, as stated in WO2021116178A1.

化合物

CDK12-IN-5
Cat.No: T40290
Synonym: CDK12-IN-5
Target:
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