Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9210 |
CD73-IN-4
|
CD73 | Immunology/Inflammation |
CD73-IN-4 是高选择性的亚甲基膦酸 CD73抑制剂,对人 CD73 作用的 IC50值为 2.6 nM,在癌症免疫学中具有研究潜力。 | |||
T35573 | Adenosine 5’-methylenediphosphate (hydrate) | ||
Adenosine 5’-methylenediphosphate is an inhibitor of ecto-5’-nucleotidase, also known as CD73, with a Kivalue of 37 nM.1It inhibits cAMP accumulation induced by adenosine 5’-monophosphate , adenosine 5’-diphosphate , or adenosine 5’-triphosphate but not adenosine in VA-13 human fibroblasts when used at a concentration of 100 μM. Adenosine 5’-methylenediphosphate reduces proliferation of U138MG glioma cells, as well as inhibits the invasion and migration of MHCC97H hepatocellular carcinoma (HCC) ... |