Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01085 |
VLDLR Protein, Human, Recombinant (His)
VLDLRCH,CAMRQ1,CHRMQ1,very low density lip... |
Human | HEK293 Cells |
The very low density lipoprotein receptor, known as VLDLR, is a single-pass type 1 integral membrance protein and a member of the LDL receptor family. This receptor family includes LDL receptor, LRP, megalin, VLDLR and ApoER2, and is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar sdomain. VLDLR contains 3 EGF-like domains, 8 LDL-receptor class A domains, as well as 6 LDL-receptor class B repeats, and is ... | |||
TMPK-00928 |
VLDLR Protein, Mouse, Recombinant (His)
CHRMQ1,VLDLR,FLJ35024,VLDLRCH,RP11 |
Mouse | HEK293 Cells |
VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures.VLDLR-CH is inherited in an autosomal recessive manner. Carrier testing for at-risk relatives, prenatal testing for a pregnancy at increased risk and preimplantation genetic testing are possible when the pathogenic variants in a family are known. |