Cat. No. | Product Name | Target | Signaling Pathways |
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T37873 | CAP 3 | ||
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces the biomass and number of colony-forming units in E. coli biofilms in a concentration-dependent manner. CAP 3 inhibits E. coli biofilm formation on catheters implanted in mice infecte... | |||
T36451 |
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)
1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt),biotin-cap-DPPE |
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1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid. It has been used in PEGylated polyamidoamine-dendrimer-conjugated supported lipid bilayers (SLB) to isolate circulating tumor cells and tumor cell microembolis from patient-derived blood by antibody-coated microfluidics. [1] It has also been used as a component of SLBs to detect protein-ligand binding with ortho-conjugated Texas Red DHPE. [2] In addition, 1,2-dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) has been used i... | |||
T64213 |
Cap-dependent endonuclease-IN-3
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Cap-dependent endonuclease-IN-3 是一种 cap-dependent 核酸内切酶 (CEN) 的有效抑制剂。Cap-dependent endonuclease-IN-3 不仅能很好地抑制流感病毒,而且具有较低的细胞毒性、较好的体内药剂动力学特性和体内药效学特性。Cap-dependent endonuclease-IN-3 对甲型和乙型流感感染表现出研究潜力。 | |||
T37105 |
2',3'-O-Isopropylideneguanosine
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2',3'-O-Isopropylideneguanosine is an alkylated guanosine building block.1,2It has been used in the synthesis of ordered honeycomb microporous films and mRNA cap analogs. 1.Gao, Y.-F., Huang, Y.-J., Xu, S.-Y., et al.Ordered honeycomb microporous films from self-assembly of alkylated guanosine derivativesLangmuir27(6)2958-2964(2011) 2.Kore, A.R., Shanmugasundaram, M., and Vlassov, A.V.Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analogBioorg. Med. Chem. Lett.1... | |||
T74586 | M7G(3'-OMe-5')pppA(2'-OMe) | ||
M7G(3'-OMe-5')pppA(2'-OMe) 是一种帽子类似物,用于 mRNA 的体外合成。 | |||
T74470 | 3'Ome-m7GpppAmpG ammonium | ||
3'Ome-m7GpppAmpG ammonium 是一种三核苷酸帽类似物,含锁核酸(LNA)分子,具显著翻译效率。作为潜在的分子生物学工具,3'Ome-m7GpppAmpG ammonium 在mRNA疫苗、mRNA转染领域应用广泛,涵盖蛋白质生产、基因治疗以及抗癌免疫等方面。 | |||
T74469 |
3'Ome-m7GpppAmpG
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3'Ome-m7GpppAmpG为具有锁核酸(LNA)分子的三核苷酸帽类似物,显示出显著的翻译效率。作为mRNA疫苗和mRNA转染领域的潜在分子生物学工具,3'Ome-m7GpppAmpG适用于蛋白质生产、基因治疗和抗癌免疫等应用。 |