搜索结果

Search Results for " bilirubin "

抑制剂 & 化合物

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T35980	Bilirubin Conjugate (sodium salt)
	Bilirubin conjugate is a stable, water-soluble ditaurate derivative of bilirubin meant to mimic endogenous bilirubin glucuronide derivatives. In vivo, bilirubin circulates in the plasma and is taken up by hepatocytes and conjugated to one or two glucuronic acids in a reaction catalyzed by UDP glucuronidase to form bilirubin mono or diglucuronide. This water-soluble form is then excreted from the liver in bile in the feces or is converted to urobilinogen and excreted in the urine. In addition to ...
T76141	Bilirubin oxidase
	Bilirubin oxidase (BOD) 为一多铜氧化酶，能催化胆红素氧化为胆绿素，同时将分子氧还原成水。该酶在卟啉及叶绿素代谢中起作用，并作为氧还原催化剂在生化研究中广泛应用。
T32951	Lumirubin
	Lumirubin is a water-soluble photoproduct of bilirubin formed in vivo during phototherapy.
T73899	Uridine diphosphate glucuronic acid ammonium
	Uridine diphosphate glucuronic acid (UDP-GlcA) ammonium 是一种由 UDP-葡萄糖脱氢酶催化生成的辅助因子，属于糖核苷酸生物合成的关键前体。它不仅是 C4 表聚酶和脱羧酶释放 UDP-半乳糖醛酸(UDP-GalA)和 UDP-戊糖产物的共同底物，而且作为葡萄糖醛酸供体，在胆红素在内质直肠结合的研究中有重要应用。
T36055	Nitisinone-13C6 Nitisinone-13C6
	Nitisinone-13C6is intended for use as an internal standard for the quantification of nitisinone by GC- or LC-MS. Nitisinone is an inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), which converts 4-hydroxyphenylpyruvate (HPPA) to homogentisate in the tyrosine catabolic pathway.1Nitisinone increases urinary levels of HPPA and 4-hydroxyphenyllactate (HPLA) in rats when administered at a dose of 10 mg/kg. Nitisinone (3 mg/kg) prevents the neonatal lethality of fumarylacetoacetate hydrolase (F...
T36864	GRP (human) (trifluoroacetate salt)
	Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend...

化合物

Bilirubin Conjugate (sodium salt)

Uridine diphosphate glucuronic acid ammonium

Synonym: Nitisinone-13C6

Target:

GRP (human) (trifluoroacetate salt)

Cat.No: T36864

Synonym:

Target:

Cat. No.	Product Name	Target	Signaling Pathways
T2934	Bilirubin 胆红素,Bilibubin,Principal bile pigment,Hematoidin,Hemetoidin	Endogenous Metabolite	Metabolism
	Bilirubin (Principal bile pigment) 是血红素分解代谢产生的黄色产物，是肝功能的重要指标。Bilirubin 具有抗诱变和抗氧化作用。
TJO2758	D-Glucuronic acid D-葡萄糖醛酸,Aldehydo-D-Glucuronic Acid	Others; Endogenous Metabolite	Metabolism; Others
	D-Glucuronic acid (Aldehydo-D-Glucuronic Acid) 是一种从许多树胶中分离出的重要中间体。它对皮肤具有抗炎作用。它及其衍生物葡萄糖醛酸内酯作为预防人类健康的肝脏解毒剂。
T35981	Biliverdin hydrochloride	Antioxidant	oxidation-reduction
	Biliverdin hydrochloride 是一种由血红素氧化形成的四吡咯水溶性化合物，具有潜在的抗氧化活性，参与胆绿素-胆红素氧化还原系统。