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Search Results for " beta-trypsin "

3

抑制剂 & 化合物

6

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T68474	RWJ-58643 HCl
	RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher doses of RWJ-58643 (300 and 600 microg) caused a late eosinophilia and preceding increases in IL-5 compared with placebo.
T38052	CRA-2059 TFA
	CRA-2059 is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 has the potential for inflammatory bowel disease research[1]. [1]. Tremaine WJ, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Aliment Pharmacol Ther. 2002;16...
T38051	CRA-2059 hydrochloride
	CRA-2059 hydrochloride is a highly specific and selective tryptase inhibitor, with a Ki of 620 pM for recombinant human tryptase-β (rHTβ)[1][2]. Tryptase is a trypsin-like serine protease found as a major protein component in human mast cell secretory granules. CRA-2059 hydrochloride has the potential for inflammatory bowel disease research[1]. [1]. Tremaine WJ, et al. Treatment of mildly to moderately active ulcerative colitis with a tryptase inhibitor (APC 2059): an open-label pilot study. Ali...

化合物

Cat.No: T68474

Cat.No: T38052

CRA-2059 hydrochloride

Cat.No: T38051

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-00484	Cationic trypsin Protein, Canine, Recombinant (His & SUMO) TRP1,Serine protease 1,PRSS1,TRY1,Pretrypsinogen I,...	Canine	E. coli
	Cationic trypsin Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-03243	Anionic trypsin-1 Protein, Rat, Recombinant (His) Pretrypsinogen I,Anionic trypsin I,Try1,Tr...	Rat	P. pastoris (Yeast)
	N/A. Anionic trypsin-1 Protein, Rat, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 23.1 kDa and the accession number is P00762.
TMPH-03242	Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) Pretrypsinogen I,Cationic trypsinogen,Try1...	Rat	E. coli
	N/A. Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 27.2 kDa and the accession number is P00762.
TMPJ-01204	TPSAB1 Protein, Human, Recombinant (His) TPS1,tryptase alpha/beta 1,TPS2,tryptase α/β1,trypt...	Human	HEK293 Cells
	Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(TPSAB1), also known as mast cell protease 7 (MCPT7), it exhibits anticoagulant activity due to its ability to degrade fibrinogen in the presence of a diverse array of protease inhibitors in plasma. The two Isoform 1 and isoform 2 are expressed in lung, stomach, spleen, heart and s...
TMPH-02408	SPI Protein, Lentinula edodes, Recombinant (His)	Lentinula edodes	E. coli
	Serine protease inhibitor. Active against beta-trypsin and alpha-chymotrypsin with dissociation constants of 0.35 nM and 40 nM respectively. Inhibits factor XIa, but not other enzymes involved in coagulation and fibrinolysis. Does not inhibit subtilisin, lysyl endopeptidase, arginyl endopeptidase or papain.
TMPH-03106	Coagulation factor XII Protein, Pig, Recombinant (His) HAF,Hageman factor,F12,Coagulation factor XII	Sus scrofa (Pig)	E. coli
	Factor XII is a serum glycoprotein that participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then trypsin cleaves it to beta-factor XIIa. Alpha-factor XIIa activates factor XI to factor XIa. Coagulation factor XII Protein, Pig, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predic...

重组蛋白

Cationic trypsin Protein, Canine, Recombinant (His & SUMO)

Cat.No: TMPH-00484

Species: Canine

Expression System: E. coli

Anionic trypsin-1 Protein, Rat, Recombinant (His)

Cat.No: TMPH-03243

Species: Rat

Expression System: P. pastoris (Yeast)

Anionic trypsin-1 Protein, Rat, Recombinant (E. coli, His)

Cat.No: TMPH-03242

Species: Rat

Expression System: E. coli

TPSAB1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-01204

Species: Human

Expression System: HEK293 Cells

SPI Protein, Lentinula edodes, Recombinant (His)

Cat.No: TMPH-02408

Species: Lentinula edodes

Expression System: E. coli

Coagulation factor XII Protein, Pig, Recombinant (His)

Cat.No: TMPH-03106

Species: Sus scrofa (Pig)

Expression System: E. coli

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