Cat. No. | Product Name | Target | Signaling Pathways |
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T30601 | BTC | ||
BTC is a human G-quadruplexes regulator, inducing dynamic transitions between the ensembles of unfolded conformations to the folded state in G-quadruplexes, altering the rod shaped DNA sequences into globular quadruplexes with a decrease in hydrodynamic r | |||
T37188 |
BTC AM
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BTC AM is a cell-permeable acetoxy-methyl ester of BTC . As BTC AM enters cells, it is hydrolyzed by intracellular esterases to produce BTC. BTC is a low affinity calcium indicator (Kd = 7-26 μM) that displays excitation/emission spectra of 401/529 nm, respectively. It exhibits a shift in the excitation maximum from approximately 480 to 401 nm upon calcium binding, enabling determination of ratiometric calcium measurements. BTC is suitable for detecting elevated calcium levels associated with ac... | |||
T82811 |
BTC tetrapotassium
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BTC tetrapotassium是一种钙指示剂,其Kd值约为7-26 µM,表现出低亲和力。它拥有适合细胞钙成像的特性,如长激发波长(400/485 nm),低对Mg2+的灵敏度,以及用于比率测量的高准确性。 | |||
T37189 |
BTCP maleate
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BTCP 与豚鼠脑膜一起预孵育可增加 [3H]TCP 从 PCP 位点的解离速率。 | |||
T24857 |
TBTC
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TBTC is a selective agonist of retinoid X receptor α that acts by improving behavioral deficit in Alzheimer's disease model mice. | |||
T82810 |
BTCy
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BTCy为一种近红外(NIR)荧光探针,表现出极性响应并具有针对细胞质膜的靶向性。适用于体内肿瘤组织成像(λex= 561 nm, λem= 600-700 nm)。 | |||
T39286 | Br-PBTC | ||
Br-PBTC is a highly potent, 2/4 subtype-selective positive allosteric modulator of nicotinic acetylcholine receptors (nAChRs). It specifically targets α2β2, α2β4, α4β2, α4β4, (α4β2)2α4, and (α4β2)2β2 subtypes of nAChRs, with EC50 values ranging from 0.1 to 0.6 μM. Br-PBTC exerts its activity by binding to the c-tail region of an α subunit. | |||
T37761 |
Fura-FF (potassium salt)
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Fura-FF is a difluorinated derivative of the calcium indicator fura-2. Unlike, fura-2, fura-FF has negligible magnesium sensitivity, thus reducing interference from this cation.[1] Fura-FF also has a higher calcium dissociation constant than fura-2 (Kd(calcium) = 6 and 0.14 μM, respectively).[1],[2]However, the spectral properties of fura-FF and fura-2 are similar with fura-FF displaying excitation/emission spectra of 365/514 nm in the absence of calcium, with a shift to 339/507 nm in the presen... |