Cat. No. | Product Name | Target | Signaling Pathways |
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T69921 |
BRF110
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BRF110 is a brain penetrant, potent and selective agonist of nuclear receptor-related 1 (Nurr1):Retinoid X receptor α (RXRα) heterodimer. BRF110 is a neuroprotective agent that prevents dopaminergic neuron demise and striatal dopaminergic denervation in vivo against PD-causing toxins. It induced dopamine biosynthesis in vivo. BRF110 chronic dosing does not induce dyskinesia in mice model. | |||
T69920 |
SAS-0132
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SAS-0132 is a modulator/antagonist of sigma2R/TMEM97 and has potential for treating TBIs, Alzheimer's disease, and neuropathic pain. |