Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T23808 |
BMS-986169
|
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BMS-986169 is a GluN2B Receptor Negative Allosteric Modulator. BMS-986169 showed a high binding affinity for the GluN2B subunit allosteric modulatory site (Ki: 4.03-6.3 nM) and selectively inhibited GluN2B receptor function in Xenopus oocytes expressing h | |||
T14686 |
BMS-986163
|
Others | Others |
BMS-986163 is a negative allosteric modulator of GluN2B and the prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM). |