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Cat. No. | Product Name | Target | Signaling Pathways |
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T71026 |
MC2050 HCl
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MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells. |
Cat. No. | Product Name | Species | Expression System |
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TMPY-01829 |
CD83 Protein, Human, Recombinant (His)
BL11,HB15,CD83 molecule |
Human | HEK293 Cells |
CD83 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is Q01151-1. | |||
TMPK-00500 |
CD83 Protein, Cynomolgus, Recombinant (His)
CD83,HB15,CD83 molecule,BL11 |
Cynomolgus | HEK293 Cells |
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising immune modulator with therapeutic potential, some important aspects such as its ligand/s, intracellular signaling pathways and modulators of its expression are unclear. |