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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T71026 MC2050 HCl

MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.

化合物

MC2050 HCl
Cat.No: T71026
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01829 CD83 Protein, Human, Recombinant (His)

BL11,HB15,CD83 molecule

Human HEK293 Cells
CD83 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.5 kDa and the accession number is Q01151-1.
TMPK-00500 CD83 Protein, Cynomolgus, Recombinant (His)

CD83,HB15,CD83 molecule,BL11

Cynomolgus HEK293 Cells
CD83 is a member of the immunoglobulin (Ig) superfamily and is expressed in membrane bound or soluble forms. Membrane CD83 (mCD83) can be detected on a variety of activated immune cells, although it is most highly and stably expressed by mature dendritic cells (DC). While CD83 is emerging as a promising immune modulator with therapeutic potential, some important aspects such as its ligand/s, intracellular signaling pathways and modulators of its expression are unclear.

重组蛋白

CD83 Protein, Human, Recombinant (His)
Cat.No: TMPY-01829
Species: Human
Expression System: HEK293 Cells
CD83 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-00500
Species: Cynomolgus
Expression System: HEK293 Cells
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