Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14554 |
BI-0252
|
Others | Others |
BI-0252 is an inhibitor of MDM2-p53 (IC50:4 nM). BI-0252 can induce tumor regressions in all animals of a mouse SJSA-1 xenograft. And it concomitant induction of the tumor protein p53 (TP53) target genes and markers of apoptosis. |