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Cat. No. Product Name Target Signaling Pathways
T18704 SPDH

Others Others
SPDH is a cleavable antibody-drug conjugate (ADC) linker utilized for the diagnosis and therapy of cancer as well as B cell proliferative diseases.
T18717 SPDV

Others Others
SPDV is a cleavable antibody-drug conjugate (ADC) linker utilized in the diagnostic and therapeutic management of cancer and B cell proliferative diseases.
T41146 ND1-YL2

ND1-YL2

ND1-YL2 is a peptide-based PROTAC®Degrader of steroid receptor co-activator 1 (SRC-1; also known as nuclear receptor coactivator 1, NCOA1). ND1-YL2 is composed of a stapled peptide that binds SRC-1 (YL2) joined by a linker to a tetrapeptide that binds UBR box domains. Upon ternary complex formation, SRC-1 is polyubiquitinated and subsequently degraded via the N-degron pathway. This Degrader induces dose-dependent degradation of SRC-1 in the MDA-MB-231 triple negative breast cancer cell line (DC5...

化合物

SPDH
Cat.No: T18704
Synonym:
Target: Others
SPDV
Cat.No: T18717
Synonym:
Target: Others
ND1-YL2
Cat.No: T41146
Synonym: ND1-YL2
Target:
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