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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T62012 Antiproliferative agent-8

Antiproliferative agent-8 (Compound 5a) 是一种抗癌化合物,显示抗增殖活性。Antiproliferative against-8 可以显著增加 P53 水平
T83022 Antiproliferative agent-33

Antiproliferative agent-33 (Compound 2g) 为抗增殖、抗真菌及抗菌化合物,可抑制MDA-MB-231细胞增殖(IC50为16.38 μM),并对革兰氏阴性菌具有生长抑制作用,S. faecalis的MIC值达到8 μg/mL。

化合物

Antiproliferative agent-8
Cat.No: T62012
Synonym:
Target:
Antiproliferative agent-33
Cat.No: T83022
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T14121 Actinonin

(-)-Actinonin

Aminopeptidase Metabolism
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].

天然产物

Actinonin
Cat.No: T14121
Synonym: (-)-Actinonin
Target: Aminopeptidase
TargetMol Loading
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