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Cat. No. Product Name Target Signaling Pathways
T63281 Antileishmanial agent-11

Antileishmanial agent-11 是有效的抗利什曼原虫剂,能够作用于 Leishmania brazilensis (IC50: 28.3 μM)、Leishmania infantum (IC50: 24.8 μM) 和T. cruzi(IC50: 13.0 μM) 具有出抗原虫作用。
T37469 Sitamaquine tosylate

Sitamaquine is an antileishmanial agent.1It is active againstL. donovani,L. infantum,L. mexicana,L. braziliensis, andL. tropica(EC50s = 9.5-19.8 μM). It inhibits mitochondrial complex II, also known as succinate dehydrogenase (SDH), in a cell-free assay when used at concentrations ranging from 10 to 200 μM.2Sitamaquine (100 μM) increases intracellular levels of reactive oxygen species (ROS) and decreases intracellular ATP levels, as well as induces phosphatidylserine externalization, chromatin f...

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Antileishmanial agent-11
Cat.No: T63281
Synonym:
Target:
Sitamaquine tosylate
Cat.No: T37469
Synonym:
Target:
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