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抑制剂 & 化合物

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Cat. No. Product Name Target Signaling Pathways
T72468 Anticancer agent 25

Anticancer agent 25对 PC3细胞显示出较强的细胞毒性,IC50值为0.19μM。
T8082 NSC745887

NSC745887 (compound 25) 是一种抗癌剂, 在所有 60 种癌细胞系中均表现出剂量依赖性的增殖抑制作用。
T35680 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide

2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is an antimicrobial agent.1It is active against the Gram-negative bacteriaE. coli,P. aeruginosa, andS. marcescens(MICs = 64, 100, and 70 μg/ml, respectively), the Gram-positive bacteriaS. aureus,M. luteus, andB. cereus(MICs = 130, 100, and 50 μg/ml, respectively), and the fungiC. albicans,G. candidum,T. rubrum,F. oxysporum,A. flavus, andS. brevicaulis(MICs = 69-120 μg/ml). 2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide is also a prec...
T83680 Azurin (50-77) (P. aeruginosa) TFA

Azurin p28,p28

Azurin (50-77)是一种含铜细菌蛋白azurin的肽段,存在于P. aeruginosa中,具有细胞周期停滞、抑制癌细胞增殖和调节血管生成活性。作为VEGFR2的抑制剂(IC20约为10.7 µM),Azurin (50-77)(20 µM)能在MCF-7乳腺癌细胞中诱导G2/M期的细胞周期停滞。在50 µM的浓度下,减少MCF-7和ZR-75-1乳腺癌细胞的增殖。Azurin (50-77)以25 µM的浓度减少VEGF-A诱导的毛细管管腔形成(IC50 = 12 µM),降低人脐静脉内皮细胞(HUVECs)中与细胞膜相关的F-actin、焦点粘附激酶(FAK)和paxillin的水平,并增加胞外的血小板内皮细胞粘附分子-1(PECAM-1)的水平。在体内,Azurin (50-77)(每日10 mg/kg)在MCF-7小鼠异种移植模型中减少肿瘤体积。

化合物

Anticancer agent 25
Cat.No: T72468
Synonym:
Target:
NSC745887
Cat.No: T8082
Synonym:
Target:
2-(1-(Thiophen-2-yl)ethylidene)hydrazinecarbothioamide
Cat.No: T35680
Synonym:
Target:
Azurin (50-77) (P. aeruginosa) TFA
Cat.No: T83680
Synonym: Azurin p28,p28
Target:
Cat. No. Product Name Target Signaling Pathways
TN4291 Isofuranodiene

IL Receptor; NOS Immunology/Inflammation
Isofuranodiene protects GalN/LPS-induced liver injury in SD rats, it may be a potential functional food ingredient for the prevention and treatment of liver diseases. Isofuranodiene has anticancer activity, by inhibiting the proliferation and inducing apo

天然产物

Isofuranodiene
Cat.No: TN4291
Synonym:
Target: IL Receptor, NOS
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