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Search Results for " aminopeptidase m "

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抑制剂 & 化合物

1

天然产物

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Cat. No. Product Name Target Signaling Pathways
T9345 Aminopeptidase M

Others Others
Aminopeptidase M 抑制对多种疾病(例如高度血管化的癌症类型)具有重要意义。
T25987 Probestin

Probestin is an aminopeptidase M inhibitor, isolated from Streptomyces azureus MH663-2F6.
T32676 Leucylmethionine

Leu-met

Leucylmethionine is a substrate for aminopeptidase M.
T37062 L-Leucine-7-amido-4-methylcoumarin hydrochloride

L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase.1Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. 1.Izquierdo, M., Lin, D., O’Neill, S., et al.Development of a high-throughput screening assay to identify inhibitors of the major M17-leucyl aminopeptidase from Trypanosoma cruzi using rapidfire mass spectrometryS...

化合物

Aminopeptidase M
Cat.No: T9345
Synonym:
Target: Others
Probestin
Cat.No: T25987
Synonym:
Target:
Leucylmethionine
Cat.No: T32676
Synonym: Leu-met
Target:
L-Leucine-7-amido-4-methylcoumarin hydrochloride
Cat.No: T37062
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T14121 Actinonin

(-)-Actinonin

Aminopeptidase Metabolism
Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].

天然产物

Actinonin
Cat.No: T14121
Synonym: (-)-Actinonin
Target: Aminopeptidase
TargetMol Loading
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