Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14130 |
Adomeglivant
LY2409021 |
Glucagon Receptor | GPCR/G Protein |
Adomeglivant (LY2409021) 是一种高效的选择性胰高血糖素受体 (GluR) 变构拮抗剂,主要用于2型糖尿病的研究。 | |||
T68472 | Adomeglivant, (+)- | ||
Adomeglivant, (+)-, is a potent and selective glucagon receptor antagonist. LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes. | |||
T68471 |
(+/-)- Adomeglivant
|
||
(+/-)- Adomeglivant, also known as LY2409021, is a potent and selective glucagon receptor antagonist. LY2409021 lowers blood glucose in healthy people and in those with type 2 diabetes. Blockade of glucagon signalling in patients with type 2 diabetes is well tolerated and results in substantial reduction of fasting and postprandial glucose with minimal hypoglycaemia, but with reversible increases in aminotransferases. Inhibition of glucagon signalling by LY2409021 is a promising potential treatm... |