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Cat. No. Product Name Species Expression System
TMPK-00870 AREG Protein, Mouse, Recombinant (hFc)

AR,MGC13647,CRDGF,AREG,Amphiregulin,SDGF,AREGB

Mouse HEK293 Cells
Amphiregulin (AREG) is a ligand of the epidermal growth factor receptor (EGFR), a widely expressed transmembrane tyrosine kinase. AREG is synthesized as a membrane-anchored precursor protein that can engage in juxtacrine signaling on adjacent cells. Alternatively, after proteolytic processing by cell membrane proteases, mainly TACE/ADAM17, AREG is secreted and behaves as an autocrine or paracrine factor.
TMPK-00820 AREG Protein, Human, Recombinant (hFc)

SDGF,AR,MGC13647,AREGB,CRDGF,Amphiregulin,AREG

Human HEK293 Cells
Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF‑κB signalling pathway in pancreatic cancer cells.
TMPJ-00859 AREG Protein, Human, Recombinant

AR,CRDGF,Amphiregulin,Colorectum Cell-Derived Growth Factor,...

Human E. coli
Amphiregulin (AREG) is a single-pass membrane protein with 252 amino acids. AREG belongs to the amphiregulin family, which contains 1 EGF-like domain. AREG is expressed in a variety of tissues including ovary, placenta, lung, kidney, stomach, colon, and breast. It is related to Epidermal Growth Factor (EGF) and Transforming Growth Factor Alpha (TGF-alpha). As an EGF-related growth factor, AREG interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits...

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AREG Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00870
Species: Mouse
Expression System: HEK293 Cells
AREG Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00820
Species: Human
Expression System: HEK293 Cells
AREG Protein, Human, Recombinant
Cat.No: TMPJ-00859
Species: Human
Expression System: E. coli
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