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Cat. No. Product Name Target Signaling Pathways
T14318 ARCC-4

Others; PROTACs Others; PROTAC
ARCC-4 is an enzalutamide-based von Hippel-Lindau (VHL)-recruiting AR PROTAC and outperforms enzalutamide and it is a low-nanomolar androgen receptor (AR) degrader based on PROTAC, with a DC50 of 5 nM. ARCC-4 effectively degrades clinically relevant AR mutants associated with antiandrogen therapy[1].
T41227 ARCC 4 negative control

ARCC 4 negative control is a negative control for ARCC 4. Binds androgen receptors (AR) without inducing degradation.
T39399 ABM-14

ABM-14, a ligand for the androgen receptor (AR), is utilized as a targeting agent in PROTAC. By binding to a ligand for the von Hippel-Lindau protein (VHL) via a linker, ABM-14 forms ARCC-4, which facilitates the degradation of AR.

化合物

ARCC-4
Cat.No: T14318
Synonym:
Target: Others, PROTACs
ARCC 4 negative control
Cat.No: T41227
Synonym:
Target:
ABM-14
Cat.No: T39399
Synonym:
Target:
TargetMol Loading
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