Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7765 |
E1210
APX001A,E 1210 |
Antifungal | Microbiology/Virology |
E1210 (APX001A) 是一种口服广谱抗真菌药,可抑制真菌糖基磷脂酰肌醇的生物合成。 | |||
T11314 |
Fosmanogepix
APX001,E1211 |
Others | Others |
Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections. |