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Cat. No. | Product Name | Target | Signaling Pathways |
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T60372 |
ALDH3A1-IN-1
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ALDH3A1-IN-1 (Compound 18) 是一种有效的ALDH3A1抑制剂,IC50为 1.61 μM。ALDH3A1-IN-1 比 DEAB 更有效地对抗患者来源的原发性前列腺肿瘤上皮细胞,无论是作为单药或与多西紫杉醇联合治疗。 | |||
T60275 |
ALDH3A1-IN-2
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ALDH3A1-IN-2 (Compound 19) 作为一种高效的ALDH3A1抑制剂,其IC50值达到1.29 μM。由于醛脱氢酶 (ALDH) 在前列腺癌等多种肿瘤类型中的过表达,ALDH3A1-IN-2 显示出其在癌症疾病研究中的应用潜力。 |
Cat. No. | Product Name | Species | Expression System |
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TMPY-02299 |
ALDH3A1 Protein, Human, Recombinant (His)
ALDHIII,aldehyde dehydrogenase 3 family, m... |
Human | Baculovirus Insect Cells |
Aldehyde dehydrogenase 3A1 (ALDH3A1) is a metabolic enzyme that catalyzes the oxidation of various aldehydes. Certain types of epithelial tissues in mammals, especially those continually exposed to environmental stress (e.g., corneal epithelium), express ALDH3A1 at high levels and its abundance in such tissues is perceived to help to maintain cellular homeostasis under conditions of oxidative stress. Metabolic as well as non-metabolic roles for ALDH3A1 have been associated with its mediated resi... |