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Cat. No. Product Name Target Signaling Pathways
T70265 AL-6556

AL-6556 is a prostaglandin DP receptor agonist.
T38113 AL 6598

Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2α and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a PGD2 receptor agonist that binds to DP receptors with a Ki value of 3.2 μM and demonstrates an EC50 value of 0.80 μM in an in vitro functional assay. Designed to enhance corneal absorption, AL 6598 produces a maximum 53% drop in IOP of the ocular hypertensive monkey with a 1 μg do...

化合物

AL-6556
Cat.No: T70265
Synonym:
Target:
AL 6598
Cat.No: T38113
Synonym:
Target:
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