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Cat. No. | Product Name | Target | Signaling Pathways |
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T82880 |
Biotin-H10
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Biotin-H10,作为一种特异性抑制剂,针对前梯度蛋白2 (AGR2),其KD值为6.4 nM。此化合物能有效抑制癌细胞活力。 |
Cat. No. | Product Name | Species | Expression System |
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TMPK-00698 |
AGR2 Protein, Mouse, Recombinant (His)
AG2,HPC8,hAG-2,Anterior gradient protein <... |
Mouse | E. coli |
Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression. | |||
TMPJ-00056 |
AG-2 Protein, Human, Recombinant (His)
HPC8,AG2,AG-2,hAG-2,Anterior Grad... |
Human | HEK293 Cells |
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of E... | |||
TMPY-04205 |
AGR3 Protein, Human, Recombinant (mFc)
hAG-3,AG3,HAG3,anterior gradient 3,PDIA18,BCMP11,AG-3 |
Human | HEK293 Cells |
Anterior gradient protein (AGR) 3 is a highly related homologue of pro-oncogenic AGR2 and belongs to the family of protein disulfide isomerases. AGR3 was found in breast, ovary, prostate, and liver cancer, it is associated with the level of differentiation, slowly proliferating tumors, and more favorable prognosis of breast cancer patients. AGR3 is a specialized member of the PDI family that plays an unexpected role in the regulation of CBF and mucociliary clearance in the airway. AGR3 had been... |