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Cat. No. | Product Name | Target | Signaling Pathways |
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T26572 |
AG2034
AG-2034,AG 2034 |
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AG2034 is an inhibitor of the glycinamide ribonucleotide formyltransferase (GARFT). | |||
T29706 |
AG28262 free base
AG28262,AG-28262,AG 28262,AG-28262 besylate |
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AG28262 is a VEFG-2 inhibitor that increases serum ALT, due in part to both gene up-regulation. |
Cat. No. | Product Name | Species | Expression System |
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TMPK-00698 |
AGR2 Protein, Mouse, Recombinant (His)
AG2,HPC8,hAG-2,Anterior ... |
Mouse | E. coli |
Anterior gradient homolog 2 (AGR2) is a functional protein with critical roles in a diverse range of biological systems, including vertebrate tissue development, inflammatory tissue injury responses, and cancer progression. | |||
TMPJ-00056 |
AG-2 Protein, Human, Recombinant (His)
HPC8,AG2,AG-2,hAG |
Human | HEK293 Cells |
Anterior Gradient 2 (AGR2) is an 18-21 kDa member of the PDI family of enzymes. AGR2 is widely expressed in secretory cells, such as small intestine goblet, prostate epithelium, enteroendocrine cells, and multiple carcinoma cell types. AGR2 forms transient disulfide linkages with molecules destined for secretion, possibly aiding protein folding. Expression of AGR2 shows a positive correlation with expression of estrogen receptor in breast carcinoma and a negative correlation with expression of E... | |||
TMPJ-00717 |
BAG2 Protein, Human, Recombinant (His)
BAG-2,BAG Family Molecular Chaper... |
Human | E. coli |
BAG Family Molecular Chaperone Regulator 2 (BAG2) is a member of the Bag family whose members compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. BAG2 contains 1 BAG domain and is a important component of the HSC 70/CHIP chaperone-dependent ubiquitin ligase complex. In mammalian cells BAG1, BAG2, and BAG3 bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. |