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5

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T69351	AD2765
	AD2765, also known as AD 2845 and Sphingosylphosphoryl choline, is a novel thiourea derivative of sphingomyelin that inhibits sphingomyelin hydrolysis and synthesis, increases ceramide, and leads to cell death.
T39515	PAD2-IN-1 PAD2-IN-1
	PAD2-IN-1, a benzimidazole-based derivative, is an efficacious and specific inhibitor of protein arginine deiminase 2 (PAD2). Demonstrating remarkable selectivity, PAD2-IN-1 exhibits a 95-fold higher affinity for PAD2 in comparison to PAD4 and a 79-fold higher affinity than PAD3.
T11406	TT-OAD2 free base	Others	Others
	TT-OAD2 free base has the potential for diabetes treatment. TT-OAD2 free base is a non-peptide glucagon-like peptide-1 (GLP-1) receptor agonist with an EC50 of 5 nM.
T63601	PAD2-IN-1 hydrochloride
	PAD2-IN-1 hydrochloride 是有效的、选择性的蛋白精氨酸脱亚氨酶 2 (PAD2) 抑制剂，且对 PAD2 的选择性优于 PAD4 (95 倍) 和 PAD3 (79 倍)，是一种基于苯并咪唑的衍生物。
T13218	TT-OAD2	Others	Others
	TT-OAD2 is a non-peptide agonist of glucagon-like peptide-1 (GLP-1) receptor (EC50: 5 nM), with the potential for diabetes treatment.

化合物

Cat.No: T69351

Cat.No: T39515

Synonym: PAD2-IN-1

TT-OAD2 free base

Cat.No: T11406

Target: Others

PAD2-IN-1 hydrochloride

Cat.No: T63601

Cat.No: T13218

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) LPG,apolipoprotein E,ApoE4,APO-E,LDLCQ5,AD2	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated APO-E,LDLCQ5,LPG,ApoE4,AD2,apolipoprotein ...	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPY-03291	SMAD2 Protein, Mouse, Recombinant (His & GST) mMad2,Smad-2,712	Mouse	Baculovirus Insect Cells
	SMAD2 is a member of the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD2 mediates the signal of the TGF-beta, and therefore regulates multiple cellular processes, such as cell proliferation, apoptosis, and differentiation. SMAD2 is recruited to the TGF-beta receptors through its interaction with the SMAD anchor for receptor activation (SARA) protein...
TMPH-01699	SMAD2 Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3...
TMPY-02238	MAD2L1 Protein, Human, Recombinant (His) MAD2 mitotic arrest deficient-like 1 (yeas...	Human	E. coli
	Mitotic spindle assembly checkpoint protein MAD2A, also known as HsMAD2, Mitotic arrest deficient 2-like protein 1, MAD2-like protein 1, MAD2L1, and MAD2, is a nucleus and cytoplasm protein that belongs to the MAD2 family. MAD2L1 is a component of the spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is required for the execution of the mitotic checkpoint which monitors the process of kinetochore-spindle atta...
TMPH-03192	NAD2 Protein, Psoroptes ovis, Recombinant (His)	Psoroptes ovis	E. coli
	N/A. NAD2 Protein, Psoroptes ovis, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 32.7 kDa and the accession number is A0A075XDS2.
TMPH-02300	RAD23A Protein, Human, Recombinant (His)	Human	E. coli
	Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. Proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome.; Involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucle...
TMPH-02225	TEAD2 Protein, Human, Recombinant (His & Myc)	Human	E. coli
	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expr...

重组蛋白

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)

Cat.No: TMPY-05297

Species: Human

Expression System: E. coli

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated

Cat.No: TMPY-05528

Species: Human

Expression System: E. coli

SMAD2 Protein, Mouse, Recombinant (His & GST)

Cat.No: TMPY-03291

Species: Mouse

Expression System: Baculovirus Insect Cells

SMAD2 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-01699

Species: Human

Expression System: E. coli

MAD2L1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02238

Species: Human

Expression System: E. coli

NAD2 Protein, Psoroptes ovis, Recombinant (His)

Cat.No: TMPH-03192

Species: Psoroptes ovis

Expression System: E. coli

RAD23A Protein, Human, Recombinant (His)

Cat.No: TMPH-02300

Species: Human

Expression System: E. coli

TEAD2 Protein, Human, Recombinant (His & Myc)

Cat.No: TMPH-02225

Species: Human

Expression System: E. coli

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