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Cat. No. Product Name Target Signaling Pathways
T71974 ABI-274

ABI-274 is a novel potent colchicine binding site inhibitor (CBSI) and tubulin inhibitor.
T71119 Netarsudil free base

Netarsudil, also known as AR-11324, is a Rho-associated protein kinase inhibitor. Netarsudil is potential useful for treating glaucoma and​/or reducing intraocular pressure. Netarsudil Increases Outflow Facility in Human Eyes Through Multiple Mechanisms. Netarsudil inhibited kinases ROCK1 and ROCK2 with a Ki of 1 nM each, disrupted actin stress fibers and focal adhesions in TM cells with IC50s of 79 and 16 nM, respectively, and blocked the profibrotic effects of TGF-β2 in HTM cells. Netarsudi...

化合物

ABI-274
Cat.No: T71974
Synonym:
Target:
Netarsudil free base
Cat.No: T71119
Synonym:
Target:
TargetMol Loading
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