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Cat. No. Product Name Target Signaling Pathways
T38323 A-943931 (hydrochloride hydrate)

A-943931 is a histamine H4receptor antagonist (Ki= 3.8 nM).1In vivo, A-943931 inhibits scratching induced by clobenpropit in mice (ED50= 26 μmoles/kg, i.p.). 1.Milicic, I., Witte, D.G., Miller, T.L., et al.Identification of two potent and selective histamine H4 receptor antagonists with antipruritic activityFASEB J.23(S1)760.768-760.768(2009)
T36779 NG 25 (hydrochloride hydrate)

NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinases (IC50s = 75.2 nM), as well as CSK, FER, and p38α (IC50s = 56.4, 82.3, and 102 nM, respectively). NG 25 (100 nM) prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectiv...
T8404 Kasugamycin hydrochloride hydrate

Ksg (hydrochloride hydrate),春雷霉素盐酸盐一水合物

Antibacterial; Antibiotic Microbiology/Virology
Kasugamycin hydrochloride hydrate (Ksg (hydrochloride hydrate)) 是一种能结合 30s 和 70s 核糖体,但不能结合 50s 亚基的抗生素。它模拟 mRNA 核苷酸破坏 tRNA 结合并抑制典型翻译起始。
T73352 A-943931

A-943931 是一种有效的选择性组胺 H4 受体拮抗剂,对人和大鼠 H4R 的 Ki 值分别为 4.6、3.8 nM。A-943931 具有抗炎和抗伤害作用。

化合物

A-943931 (hydrochloride hydrate)
Cat.No: T38323
Synonym:
Target:
NG 25 (hydrochloride hydrate)
Cat.No: T36779
Synonym:
Target:
Kasugamycin hydrochloride hydrate
Cat.No: T8404
Synonym: Ksg (hydrochloride hydrate),春雷霉素盐酸盐一水合物
Target: Antibacterial, Antibiotic
A-943931
Cat.No: T73352
Synonym:
Target:
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