Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37793 |
A2B receptor antagonist 2
A2B receptor antagonist 2 |
Adenosine Receptor | GPCR/G Protein; Neuroscience |
A2B receptor antagonist 2 是腺苷受体 A2B 的拮抗剂(rA1 的 Ki = 2.30 μM,rA2A 的 Ki = 6.8 μM,hA2B 的 3.44 μM)。 | |||
T26781 |
BF-1
BF1 |
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BF-1 is a 5-Hydroxytryptamine receptor 2B antagonist. BF-1 was tested as potential migraine prophylactic drug by blocking BW723C86 (5-((thiophen-2-yl)methoxy)-α-methyltryptamine) or meta-chlorophenylpiperazine (mCPP) induced neurogenic dural plasma protei | |||
T60580 |
A1AR antagonist 2
|
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A1AR antagonist 2 (compound 18h) 是 A1腺苷受体 (A1 adenosine receptor) 的有效的选择性拮抗剂。A1AR antagonist 2对于 hA1, hA2A,hA2B 的Ki 值分别为 1.49、10.2 和 50.1 nM。 | |||
T21558 |
MK-3207
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MK-3207是口服生物相容性的CGRP 受体拮抗剂,IC50和 Ki 分别为 0.12 nM 和 0.024 nM,对 AM1,AM2,CTR 和 AMY3 的抑制性较弱。MK-3207可用于偏头痛研究。 |